The investigation of complex endometrial hyperplasia prevalence by diagnostic curettage and some of riskfactors affiliated to it in ahvaz-razi hospital

Author(s): Ali Ghomeishi, Mahin Najafian*


The endometrial hyperplasia indicates the wide spectrum of limit variation of endometrial hyperplasia which has changed from intensification of physiological status to carcinoma. The endometrial hyperplasia is the introduction of the endometrial cancer, which is the most common female genital tract malignancy. Studies suggest that abnormal uterine bleeding is the most common indication of the endometrial hyperplasia that is performed for diagnosis of diagnostic curettage. With regard to the mentioned issue of this study, in order to identify factors associated with endometrial hyperplasia have been performed. This cross-sectional study has been performed on one thousand diagnostic curettage specimen’s from 1390 to 1393 (During the last three years) in RaziAhvaz hospital. The specimens based on the presence or absence of endometrial hyperplasia were divided into two groups. Then factors such as age, menstrual pattern, diabetes, hypertension, history of infertility, age over 45years, obesity, use of oral contraceptives were studied and compared. In this study of a thousand cases of diagnostic curettage, because of abnormal uterine bleeding in 160 patients(16%) complex hyperplasia, with factors such as oligomenorrhea38% vs.8/5 % (P<0/0001) and diabetes (28%) versus (P<0/001), hypertension 32% versus 12% (P<0/001), history of infertility, 19% vs. 5/5% (P<0/001), age over 45years, 32% versus 19% (P<0/001), obesity BMI> 30 46% versus 18% (P<0/001), nulliparity 9% versus 1% (P<0/001) had significant relationship with endometrial hyperplasia. But there was no significant relationship with use of oral contraceptive. According to this study, women who were obese and have history of hypertension, diabetes, infertility, menstrual disorders as oligomenorrhea are at high risk for developing endometrial hyperplasia which at last leads to endometrial cancer.

image 10.21746/ijbio.2015.01.0017

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