Prevalence of thyroid dysfunction in Rayalaseema region ��? post iodization scenario.

Author(s): Pandit Vinodh B.*, Durga Prasad K., Havilah P.

Abstract

Rayalaseema is an endemic area for iodine deficiency. Also consumption of sea food is deficient in this region. Hence, it raises a question of thyroid dysfunction prevalence in this region. There are no recent scientific reports on the prevalence of thyroid disorders in Rayalaseema region in Andhra Pradesh. The present study was designed with an objective to assess the prevalence of thyroid dysfunction in post iodization phase. 700 subjects (373 females, 327 males) who have fulfilled the selection criterias were taken into current study. The subjects were analyzed for levels of tri-iodothyronine (T3), tetra-iodothyronine (T4), and thyroid stimulating hormone (TSH). Based on their TSH levels subjects were divided into four groups: 60% euthyroid, 10.57% hypothyroid, 22.14% subclinical hypothyroid and 7.28% were hyperthyroid. Prevalence of thyroid dysfunction was 40% includes 62.28% females and 30.71% males. In the thyroid disorders, prevalence of overt hypothyroidism was 24.42%, subclinical hypothyroidism 55.35% and overt hyperthyroid 18.21%. The prevalence of thyroid dysfunction was 40% in Rayalaseema region, post iodization scenario. Subclinical hypothyroidism was the highly prevalent thyroid dysfunction in Rayalaseema region. Subclinical hypothyroidism was highly prevalent thyroid dysfunction in Rayalaseema region. This study recommends sensitive estimation of TSH level as a routine parameter in clinical check-up of Rayalaseema region population. This will help to detect thyroid dysfunction in most the cost effective way at an early stage and eradicate associated comorbidities in this region.

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